King Gilgamesh has died of overwork and exhaustion...
Stunned, Fujimaru and his companions are thrown into utter confusion. Siduri informs them that, besides King Gilgamesh, an increasing number of Uruk’s citizens are growing weaker and dying.
The group concludes that the Mistress of the Underworld, one of the deities of the Three Goddess Alliance, is the cause of all this. To defeat this goddess and liberate King Gilgamesh’s soul, they must travel to the underworld itself...